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6th International Metaproteomics Symposium

Monday 13th January

09:00 - 10:00

Registration and coffee, poster setup

10:00 - 10:15

Opening of the 6th IMS 2025

Anchor Monday

Session 1: New methods and trends in metaproteomics

Chairs: Lucia Grenga and Pratik Jagtap

10:15 - 11:00

INVITED LECTURE

Advanced Metaproteomics Approaches to Investigate Diet-Host-Microbiota Interactions

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Manuel Kleiner (North Carolina State University, Raleigh, USA)

11:00 - 11:15

Assessment of DIA methods for metaproteomics - Challenges and opportunities

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Benoit J. Kunath (University of Luxembourg)

11:15 - 11:30

FASTA Lake: Multi-Omics Framework Reveals Host-Microbe Dynamics in Acute Decompensation of Cirrhosis

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Peter Treit (Max Planck Institute for Biochemistry)

11:30 - 11:45

Gold sponsor talk

An ultra-sensitive Metaproteomic solution (uMetaP) redefines the “dark” microbiome, reaches single-bacterium resolution and discovers Host-Microbiota interactions during metabolic injury in-vivo.

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David Gomez Varela (Center of Excellence for Metaproteomics University of Vienna - Bruker)

11:45 - 12:00

Quick leg stretch

12:00 - 12:15

Advancing de novo metaproteomics with Kaiko 2.0.

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Camilo Posso (Pacific Northwest National Lab)

12:15 - 12:30

Characterization of extracellular vesicles of intestinal microbiota using metaproteomics in patients with Crohn's disease.

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Celine Henry (University Paris-Saclay, INRAE)

12:30 - 12:45

Creating microbiome-model harmony between metaproteomics data and the ADM1da model for a two-step anaerobic digester

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Patrick Hellwig (Otto von Guericke University Magdeburg)

12:45 - 14:00

Lunch, poster setup in poster hall

Session 2: Animal microbiome and holo-omics

Chairs: Veronika Pettersen and Live H. Hagen

14:00 - 14:45

INVITED LECTURE

Metaproteome plasticity: cause or effects?

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Itzhak Mizrahi (Ben-Gurion University of the Negev, Israel)

14:45 - 15:00

Metaproteomics as a contributor to understanding rumen microbiome patterns

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Velma Aho (Norwegian University of Life Sciences)

15:00 - 15:15

Spirochetes in marine invertebrates: adversaries or allies?

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Grace D'angelo (Max Planck Institute for Marine Microbiology)

15:15 - 15:45

Coffee, refreshments, group photo in sunset

15:45 - 16:00

Metaproteomics to investigate host-microbiota responses in a non-model sentinel species to environmental factors

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Thibaut Dumas (Commissariat à l'Energie Atomique et aux Energies Alternatives, CEA)

16:00 - 16:15

Discovery of plastic degrading enzymes from the mealworm microbiome using metaproteomics and meta-chemoproteomics

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Harrison Hall (Baylor University)

16:15 - 17:30

Poster session

17:30

Norwegian bonfire & blackcurrant toddy

Anchor Tuesday

Tuesday 14th January

08:30 - 09:00

Registration and coffee

Session 3: Environmental microbiome

Chairs: Jean Armengaud and Magnus Ø. Arntzen

09:00 - 09:45

INVITED LECTURE

Unlocking marine microbial dynamics: metaproteomic approaches to tackle global pollution

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Sabine Matallana-Surget (University of Stirling, UK)

09:45 - 10:00

Temporal dynamics of bacterial species and CAZYmes involved in lignocellulose degradation by microbial consortia enriched from cow rumen and termite gut

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Guillermina Hernandez Raquet (Toulouse Biotechnology Institute INRAE)

10:00 - 10:15

Metagenome-centric metaproteomic profiling of microbial dynamics in a full-scale biogas plant fed fish-ensilage

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Thea Andersen (Norwegian University of Life Sciences)

10:15 - 10:30

Microbial interactions in a high-performance tubular foam-bed reactor for biomethanation

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Dirk Benndorf (Anhalt University of Applied Sciences)

10:30 - 11:00

Coffee, visit poster hall

11:00 - 11:45

INVITED LECTURE

Uncovering microbial mysteries: novel peptide sequencing to explore ecosystems across time and space

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Emma Timmins-Schiffman (University of Washington, Seattle, USA)

11:45 - 12:00

Profiling the Mushroom Microbiome: Impacts on Developmental and Disease Outcomes through Devome Manipulation

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Eoin O'Connor (The Pennsylvania State University)

12:00 - 12:15

Metaproteomic profiling of the secretome of a granular biofilm forming enrichment

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Berdien Van Olst (Delft University of Technology)

12:15 - 12:30

Gold sponsor presentation

Sample preparation and 4D-omics approaches for metaproteomics

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Pierre-Olivier Schmit (Bruker Daltonics GmbH & Co. KG)

12:30- 13:45

Lunch

Session 4: Integrative multi-omics and bioinformatics

Chairs: Tjorven Hinzke and Tim Van Den Bossche

13:45 - 14:00

The Peptonizer2000: Confident Taxonomic Insights, Now Just a Click Away!

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Tanja Holstein (Ghent University)

14:00 - 14:15

Unipept in 2024: Expanding Metaproteomics Analysis with Support for Missed Cleavages, Semi-Tryptic and Non-Tryptic Peptides

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Pieter Verschaffelt, Vande Moortele Tibo (Ghent University)

14:15 - 14:30

MetaPepView: a web interface for visualization and evaluation of metaproteomic data

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Ramon Van Der Zwaan (Delft University of Technology)

14:30 - 14:45

Evaluation of statistical approaches for differential metaproteomics

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Tjorven Hinzke (University of Greifswald)

14:45 - 15:00

MetaLab Platform Enables Comprehensive DDA and DIA Metaproteomics Analysis

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Kai Cheng (University of Ottawa)

15:00 - 15:30

Coffee, refreshments, visit poster hall

15:30 - 15:45

Increased insight into metaproteomics data obtained by advanced bioinformatics tools and modeling

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Robert Heyer (ISAS Dortmund/ Universität Bielefeld)

15:45 - 16:00

Metadata in metaproteomics: integrating MIxS into SDRF-Proteomics

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Tim Van Den Bossche (VIB - Ghent University)

OPEN DISCUSSION

Chairs: Robert Hettich & Benoit Kûnath

16:00 - 17:30

Status of CAMPI challenges and future directions​

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Metaproteomics Initiative and next IMS

20:00

Conference dinner

Anchor Wednesday

Wednesday 15th January

08:30 - 09:00

Coffee

Session 5: Microbiomes in health and disease

Chairs: Mary Lipton and Sabina Leanti La Rosa

09:00 - 09:45

INVITED LECTURE

Pushing the envelope of metaproteomics for more comprehensive characterization of the human microbiome in disease

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Robert Hettich (Oak Ridge National Laboratory, Oak Ridge, USA)

09:45 - 10:00

Meta-analysis of fecal metaproteomic datasets reveals robust human and microbial signatures for inflammatory bowel disease

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Maximilian Wolf (Bielefeld University)

10:00 - 10:15

The use of probiotics to reduce antibiotic resistance gene carriage in the infant gut

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Veronika Pettersen (UiT Arctic University of Norway)

10:15 - 10:30

A new platform to study gut microbiota-derived extracellular vesicles and their impact on the host physiology through a metaproteomics approach

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Marcello Manfredi (University of Piemonte Orientale)

10:30 - 11:00

Coffee, visit poster hall, check-out

11:00 - 11:15

Airway microbiota dynamics in response to ETI therapy: a metaproteomic perspective

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Hamid Hachemi (CEA)

11:15 - 11:30

Functional biogeography of the colorectal cancer-associated microbiota

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Alessandro Tanca (University Hospital of Sassari, Sassari, Italy)

11:30 - 11:45

Metaproteomic Approach to Detect Key Host and Microbial Peptides from Oral Leukoplakia samples.

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Pratik Jagtap (University of Minnesota)

11:45 - 12:00

Metaproteomics Uncovers Distinctively Abundant Metabolic Enzymes that Exhibit Correlation With Response to Cancer Immunotherapy

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Lior Lobel (Bar-Ilan University)

12:00- 13:30

Lunch, poster dismount

AWARDS

13:30 - 14:00

Chair: Phil Pope

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Best talk award - sponsored by our Gold sponsor: Bruker

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Best poster awards - sponsored by our Silver sponsor: Cmbio

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ISME Trailblazer award to an ECR in microbial ecology

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Travel awards - sponsored by The European Proteomics Association (EuPA)

14:00 - 14:30

Best Manuscript award

Chair: Madita Brauer

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Insights into protein annotation, pathway reconstruction, and species resolved function from the paper "Dietary protein source strongly alters gut microbiota composition and function"

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Jose Alfredo Blakeley-Ruiz (North Carolina State University)

14:30

Closing of the 6th IMS 2025 meeting

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