6th International Metaproteomics Symposium
Monday 13th January
09:00 - 10:00
Registration and coffee, poster setup
10:00 - 10:15
Opening of the 6th IMS 2025
Session 1: New methods and trends in metaproteomics
Chairs: Lucia Grenga and Pratik Jagtap
10:15 - 11:00
INVITED LECTURE
Advanced Metaproteomics Approaches to Investigate Diet-Host-Microbiota Interactions
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Manuel Kleiner (North Carolina State University, Raleigh, USA)
11:00 - 11:15
Assessment of DIA methods for metaproteomics - Challenges and opportunities
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Benoit J. Kunath (University of Luxembourg)
11:15 - 11:30
FASTA Lake: Multi-Omics Framework Reveals Host-Microbe Dynamics in Acute Decompensation of Cirrhosis
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Peter Treit (Max Planck Institute for Biochemistry)
11:30 - 11:45
Gold sponsor talk
An ultra-sensitive Metaproteomic solution (uMetaP) redefines the “dark” microbiome, reaches single-bacterium resolution and discovers Host-Microbiota interactions during metabolic injury in-vivo.
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David Gomez Varela (Center of Excellence for Metaproteomics University of Vienna - Bruker)
11:45 - 12:00
Quick leg stretch
12:00 - 12:15
Advancing de novo metaproteomics with Kaiko 2.0.
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Camilo Posso (Pacific Northwest National Lab)
12:15 - 12:30
Characterization of extracellular vesicles of intestinal microbiota using metaproteomics in patients with Crohn's disease.
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Celine Henry (University Paris-Saclay, INRAE)
12:30 - 12:45
Creating microbiome-model harmony between metaproteomics data and the ADM1da model for a two-step anaerobic digester
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Patrick Hellwig (Otto von Guericke University Magdeburg)
12:45 - 14:00
Lunch, poster setup in poster hall
Session 2: Animal microbiome and holo-omics
Chairs: Veronika Pettersen and Live H. Hagen
14:00 - 14:45
INVITED LECTURE
Metaproteome plasticity: cause or effects?
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Itzhak Mizrahi (Ben-Gurion University of the Negev, Israel)
14:45 - 15:00
Metaproteomics as a contributor to understanding rumen microbiome patterns
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Velma Aho (Norwegian University of Life Sciences)
15:00 - 15:15
Spirochetes in marine invertebrates: adversaries or allies?
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Grace D'angelo (Max Planck Institute for Marine Microbiology)
15:15 - 15:45
Coffee, refreshments, group photo in sunset
15:45 - 16:00
Metaproteomics to investigate host-microbiota responses in a non-model sentinel species to environmental factors
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Thibaut Dumas (Commissariat à l'Energie Atomique et aux Energies Alternatives, CEA)
16:00 - 16:15
Discovery of plastic degrading enzymes from the mealworm microbiome using metaproteomics and meta-chemoproteomics
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Harrison Hall (Baylor University)
16:15 - 17:30
Poster session
17:30
Norwegian bonfire & blackcurrant toddy
Tuesday 14th January
08:30 - 09:00
Registration and coffee
Session 3: Environmental microbiome
Chairs: Jean Armengaud and Magnus Ø. Arntzen
09:00 - 09:45
INVITED LECTURE
Unlocking marine microbial dynamics: metaproteomic approaches to tackle global pollution
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Sabine Matallana-Surget (University of Stirling, UK)
09:45 - 10:00
Temporal dynamics of bacterial species and CAZYmes involved in lignocellulose degradation by microbial consortia enriched from cow rumen and termite gut
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Guillermina Hernandez Raquet (Toulouse Biotechnology Institute INRAE)
10:00 - 10:15
Metagenome-centric metaproteomic profiling of microbial dynamics in a full-scale biogas plant fed fish-ensilage
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Thea Andersen (Norwegian University of Life Sciences)
10:15 - 10:30
Microbial interactions in a high-performance tubular foam-bed reactor for biomethanation
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Dirk Benndorf (Anhalt University of Applied Sciences)
10:30 - 11:00
Coffee, visit poster hall
11:00 - 11:45
INVITED LECTURE
Uncovering microbial mysteries: novel peptide sequencing to explore ecosystems across time and space
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Emma Timmins-Schiffman (University of Washington, Seattle, USA)
11:45 - 12:00
Profiling the Mushroom Microbiome: Impacts on Developmental and Disease Outcomes through Devome Manipulation
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Eoin O'Connor (The Pennsylvania State University)
12:00 - 12:15
Metaproteomic profiling of the secretome of a granular biofilm forming enrichment
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Berdien Van Olst (Delft University of Technology)
12:15 - 12:30
Gold sponsor presentation
Sample preparation and 4D-omics approaches for metaproteomics
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Pierre-Olivier Schmit (Bruker Daltonics GmbH & Co. KG)
12:30- 13:45
Lunch
Session 4: Integrative multi-omics and bioinformatics
Chairs: Tjorven Hinzke and Tim Van Den Bossche
13:45 - 14:00
The Peptonizer2000: Confident Taxonomic Insights, Now Just a Click Away!
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Tanja Holstein (Ghent University)
14:00 - 14:15
Unipept in 2024: Expanding Metaproteomics Analysis with Support for Missed Cleavages, Semi-Tryptic and Non-Tryptic Peptides
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Pieter Verschaffelt, Vande Moortele Tibo (Ghent University)
14:15 - 14:30
MetaPepView: a web interface for visualization and evaluation of metaproteomic data
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Ramon Van Der Zwaan (Delft University of Technology)
14:30 - 14:45
Evaluation of statistical approaches for differential metaproteomics
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Tjorven Hinzke (University of Greifswald)
14:45 - 15:00
MetaLab Platform Enables Comprehensive DDA and DIA Metaproteomics Analysis
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Kai Cheng (University of Ottawa)
15:00 - 15:30
Coffee, refreshments, visit poster hall
15:30 - 15:45
Increased insight into metaproteomics data obtained by advanced bioinformatics tools and modeling
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Robert Heyer (ISAS Dortmund/ Universität Bielefeld)
15:45 - 16:00
Metadata in metaproteomics: integrating MIxS into SDRF-Proteomics
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Tim Van Den Bossche (VIB - Ghent University)
OPEN DISCUSSION
Chairs: Robert Hettich & Benoit Kûnath
16:00 - 17:30
Status of CAMPI challenges and future directions​
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Metaproteomics Initiative and next IMS
20:00
Conference dinner
Wednesday 15th January
08:30 - 09:00
Coffee
Session 5: Microbiomes in health and disease
Chairs: Mary Lipton and Sabina Leanti La Rosa
09:00 - 09:45
INVITED LECTURE
Pushing the envelope of metaproteomics for more comprehensive characterization of the human microbiome in disease
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Robert Hettich (Oak Ridge National Laboratory, Oak Ridge, USA)
09:45 - 10:00
Meta-analysis of fecal metaproteomic datasets reveals robust human and microbial signatures for inflammatory bowel disease
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Maximilian Wolf (Bielefeld University)
10:00 - 10:15
The use of probiotics to reduce antibiotic resistance gene carriage in the infant gut
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Veronika Pettersen (UiT Arctic University of Norway)
10:15 - 10:30
A new platform to study gut microbiota-derived extracellular vesicles and their impact on the host physiology through a metaproteomics approach
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Marcello Manfredi (University of Piemonte Orientale)
10:30 - 11:00
Coffee, visit poster hall, check-out
11:00 - 11:15
Airway microbiota dynamics in response to ETI therapy: a metaproteomic perspective
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Hamid Hachemi (CEA)
11:15 - 11:30
Functional biogeography of the colorectal cancer-associated microbiota
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Alessandro Tanca (University Hospital of Sassari, Sassari, Italy)
11:30 - 11:45
Metaproteomic Approach to Detect Key Host and Microbial Peptides from Oral Leukoplakia samples.
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Pratik Jagtap (University of Minnesota)
11:45 - 12:00
Metaproteomics Uncovers Distinctively Abundant Metabolic Enzymes that Exhibit Correlation With Response to Cancer Immunotherapy
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Lior Lobel (Bar-Ilan University)
12:00- 13:30
Lunch, poster dismount
AWARDS
13:30 - 14:00
Chair: Phil Pope
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Best talk award - sponsored by our Gold sponsor: Bruker
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Best poster awards - sponsored by our Silver sponsor: Cmbio
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ISME Trailblazer award to an ECR in microbial ecology
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Travel awards - sponsored by The European Proteomics Association (EuPA)
14:00 - 14:30
Best Manuscript award
Chair: Madita Brauer
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Insights into protein annotation, pathway reconstruction, and species resolved function from the paper "Dietary protein source strongly alters gut microbiota composition and function"
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Jose Alfredo Blakeley-Ruiz (North Carolina State University)
14:30
Closing of the 6th IMS 2025 meeting